What do you think are the most addictive opiate drugs? Before anything else, we all think of heroin. Well, okay—that may be a given. But what about addictive opiate drugs that you can obtain as a prescription? Take a look at this list and see if you can identify the common denominator among them. What Are the Top 3 Most Addictive Opiate Drugs? Codeine. Before we all heard about hydrocodone and ...